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The pyruvate dehydrogenase complex converts pyruvate to acetyl coenzyme A, abbreviated acetyl CoA, which can then enter metabolic pathways such as the citric acid cycle. Identify the citric acid cycle enzyme that is mechanistically and structurally similar to the pyruvate dehydrogenase complex. Which enzyme or enzyme complex is similar to the pyruvate dehydrogenase complex? isocitrate dehydrogenase fumarase glyceraldehyde 3‑phosphate dehydrogenase α‑ketoglutarate dehydrogenase

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Answer:

α‑ketoglutarate dehydrogenase

Explanation:

This is an enzyme complex ,which is analogous to pyruvate dehydrogenase. . Its catalytic activity is inhibited by it products succinyl Co A,it is also refers to as oxoglutarate dehydrogenase complex.(OGDC).

This enzyme complex  is similar to pyruvate dehydrogenase in  having  the same subunit structure, and using  the same type of co-enzyme.    

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