Which of the following is a characteristic of biological transmission from Dermacentor to a human host?

1- The human host is infected after drinking water contaminated with Dermacentor eggs.
2- R. rickettsii is transmitted to the human host during a bite, when tick saliva enters the wound.
3- R. rickettsii is transmitted to the human host after the human consumes food that the tick has contacted.
4- R. rickettsii is transmitted to the human after the human drinks water that has been contaminated by feces from an animal infected with Dermacentor spp.